diff --git a/pkg/libcose/Makefile.dep b/pkg/libcose/Makefile.dep
index bab895a648..da93126dd0 100644
--- a/pkg/libcose/Makefile.dep
+++ b/pkg/libcose/Makefile.dep
@@ -2,9 +2,6 @@ USEPKG += nanocbor
 
 USEMODULE += libcose_crypt
 
-ifneq (,$(filter libcose_crypt_tweetnacl,$(USEMODULE)))
-  USEPKG += tweetnacl
-endif
 ifneq (,$(filter libcose_crypt_hacl,$(USEMODULE)))
   USEPKG += hacl
 endif
diff --git a/pkg/libcose/Makefile.include b/pkg/libcose/Makefile.include
index 744210a853..3215fa1c9f 100644
--- a/pkg/libcose/Makefile.include
+++ b/pkg/libcose/Makefile.include
@@ -1,9 +1,6 @@
 INCLUDES += -I$(PKGDIRBASE)/libcose/include
 CFLAGS += -DUSE_CBOR_CONTEXT
 
-ifneq (,$(filter libcose_crypt_tweetnacl,$(USEMODULE)))
-  CFLAGS += -DCRYPTO_TWEETNACL
-endif
 ifneq (,$(filter libcose_crypt_hacl,$(USEMODULE)))
   CFLAGS += -DCRYPTO_HACL
 endif