diff --git a/pkg/littlefs2/Makefile.include b/pkg/littlefs2/Makefile.include
index aca2d10be6..f7398fb4ef 100644
--- a/pkg/littlefs2/Makefile.include
+++ b/pkg/littlefs2/Makefile.include
@@ -4,3 +4,6 @@ DIRS += $(RIOTBASE)/pkg/littlefs2/fs
 
 # Reduce LFS_NAME_MAX to 31 (as VFS_NAME_MAX default)
 CFLAGS += -DLFS_NAME_MAX=31
+
+# avoid compilation errors when NDEBUG is defined
+CFLAGS += -DLFS_NO_ASSERT